October 2024, Illumina launched the Miseq i100 series, a benchtop powerhouse that replaces the legacy Miseq sequencers. The Miseq i100 series covers less footprint yet offers improved speed, ease of use, and sustainability in next-generation sequencing.
Built on the XLEAP-SBS (sequencing by synthesis) chemistry innovation, the Miseq i100 series improves on the legacy Miseq launched in 2011 by simplifying sequencing for everyone while incorporating the groundbreaking technology and chemistry of the NovaSeq™ X Series. The new series includes Miseq i100 and Miseq i100 Plus benchtop sequencing systems.
The XLEAP-SBS chemistry is Illumina’s fastest, most robust, and highest-quality sequencing by synthesis (SBS) chemistry to date. It is built from the proven foundation of the most widely adopted and used SBS chemistry, providing significant improvements in stability, speed, and performance across Illumina kits, delivering higher confidence in generated data and expediting project completion.
MiSeq i100 Series as compared to MiSeq System
- Simplified
The Miseq i100 series offers a three-step setup, onboard cluster generation and onboard denaturation; no post-run washes; sample-to-analysis workflows with onboard DRAGENTM analysis
- Improved Speed
The Miseq i100 series offers same-day results with runs as fast as 4 hour and < 2 hour onboard secondary analysis for most applications
- More sustainable
The Miseq i100 series offers room-temperature (RT) shipment and storage of consumables, 85% reduction in packaging waste, 35% reduction in total carbon footprint, compared to the MiSeq System
- Lower Cost of Sequencing
The Miseq i100 series offers up to 40% lower cost of consumables per run providing flexible and scalable solutions for lower throughput users.
Have confidence in your results
The MiSeq i100 and MiSeq i100 Plus Systems offer eleven different reagent configurations with read lengths up to 2 × 500 bp that support an output range of 5M–100M reads and 1.5 Gb–30Gb. The expanded output of the MiSeq i100 Series enables users to increase sample throughput readily and perform deeper sequencing for various applications.
The MiSeq i100 Series has sample-to-analysis workflows that include library prep kits, enrichment panels (where applicable), and DRAGEN secondary analysis. Comprehensive data summaries can be generated for select infectious disease, microbiology, and oncology applications in two hours or less.
- Compatible library prep kits and probe panels streamline experiment planning
- Prebuilt DRAGEN pipelines simplify analysis, minimizing bioinformatic expertise requirements
- Public data sets available for comparison of results boost confidence
Unprecedented sustainability
More science, less environmental impact. The MiSeq i100 Series incorporates groundbreaking sustainability innovations that enhance the user experience.
- RT shipping requires no dry ice and no ice packs
- RT storage of consumables does not require thawing, expediting setup and saving freezer space and energy
- Packaging waste reduced by 85%, facilitating 52% reduction in CO2 emissions from reagent shipping compared to the MiSeq System
- Total carbon footprint reduced by 35% compared to the MiSeq System
Trusted technology, trusted partner
For over a decade, the MiSeq Systems have been the most widely used NGS instruments on the market and are cited in over 160,000 peer-reviewed publications. Building on this extensive expertise, Illumina has a relentless commitment to innovation and building future NGS capabilities and applications. The MiSeq i100 Series demonstrates our commitment to increasing access to genomics technology by continuing to deliver faster, simpler sequencing.
ISN Medical, Illumina Authorised Channel Partner
Since 1981, ISN Medical has continued to solve the problem of poor patient care due to inaccurate medical diagnostics testing, and now across 21 countries in West and Central Africa. Through our partnership with innovative manufacturers like Illumina, we continue to provide high-end solutions for public health and research in Africa.
Partner with us to implement your One Health project today.
Email us: customer@isnmedical.com
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